Preclinical Epilepsy CDEs
*Created by the International League Against Epilepsy/American Epilepsy Society Joint Translational Task Force, sponsored in part by CURE Epilepsy
- CDEs in a variety of topics including core information, EEG, behavioral studies, pharmacology, physiology, and omics can be found here.
- Publications containing the above CDEs and associated case report forms (CRFs) can be found here.
Traumatic Brain Injury (TBI)/Post-Traumatic Epilepsy (PTE) CDEs
*Electronic CRFs were created as part of CURE Epilepsy’s PTE Initiative and contain CDEs sourced primarily from the NINDS CDE and Federal Interagency TBI Research (FITBIR) Informatics System databases.
- Preclinical TBI/PTE Research Electronic Data Capture (REDCAP) CDE package
- Clinical TBI/PTE Research REDCAP CDE package
*Note that you will need a REDCAP account to be able to access these CRFs. Accounts are often available through individual institutions/universities. For more information, visit the REDCAP website.
Sudden Unexpected Death in Epilepsy (SUDEP) CDEs
At the 2020 SUDEP Coalition Summit, which gathered key stakeholders to develop a roadmap toward ending SUDEP, a critical need was identified for tools and methods to better characterize and understand the clinical relevance of SUDEP animal models. To address this, the SUDEP Data Standardization Project was launched in 2022. This initiative provides a standardized framework for data collection and reporting, enabling preclinical researchers to more effectively characterize SUDEP animal models and enhance their translation to clinical applications.
These efforts were generously supported by the BAND Foundation
Thank you to our SUDEP Standardization Tools Project Working Group Members.
Please find the Case Report Forms (CRFs) and the corresponding data dictionaries for each module. If you experience an issue accessing the forms, please contact Elaine O’Loughlin at elaine.oloughlin@cureepilepsy.org
Downloadable are available with a brief tutorial embedded in each document:
- Table of Contents Case Report Form
- Core and Death-Related Information Case Report Form
- Neurological Variables Case Report Form
- Physiologic Measures Case Report Form
- Therapeutics and Pharmacology Case Report Form
- Imaging Case Report Form
- Ex Vivo/In Vitro Electrophysiology Case Report Form
- Additional Phenotypes Case Report Form
Data dictionaries for the modules can also be downloaded as csv files below:
- Core and Death Related Information Data Dictionary
- Supplementary Data Dictionaries
