April 30, 2021

Researcher Update: April/May 2021

In this month’s update, please find information on:

Accepting Letters of Intent for CURE Epilepsy Catalyst Award Starting June 1, 2021

The CURE Epilepsy Catalyst Award is available to researchers at non-academic research institutions, including small biotechnology companies, and universities who seek to develop new interventions for epilepsy. Applicants with academic appointments must be at or above the level of Assistant Professor. International applicants are welcome. Requests may be made for up to a total of $250,000 paid over 2 years.


Open call for Letters of Intent: Tuesday, June 1, 2021
Letter of Intent deadline: Wednesday, June 30, 2021, 9 PM ET
Full proposal invitations: Friday, August 6, 2021
Full proposal deadline: Friday, September 10, 2021, 9 PM ET
Anticipated awardee notification: December 2021-January 2022
Anticipated award start date: March 2022


CURE Epilepsy Online Seminar: Understanding the Mechanisms of Epilepsy in mTORopathies (FCDII and TSC)

Hyperactivation of mechanistic target of rapamycin (mTOR) signaling is implicated in a number of focal cortical malformations associated with intractable epilepsy. While the link between focal cortical malformations and epilepsy is well known, the underlying mechanisms remain unclear.

CURE Epilepsy Scientific Advisory Council member Dr. Angelique Bordey will focus on the role of hyperpolarization-activated cyclic nucleotide-gated potassium channel isoform 4 (HCN4) as an mTOR-dependent driver of epilepsy in tuberous sclerosis complex (TSC) and focal cortical dysplasia II (FCDII).

The virtual Frontiers in Research Seminar Series is sponsored by the Nussenbaum-Vogelstein Family.

NIBIB Commercializing Innovation Education Program Applications Due May 25

The NIBIB is providing an opportunity for NIBIB-funded grantees to participate in an online entrepreneurial education platform aimed at teaching academic innovators methods to assess the commercial value of their biomedical technologies through its commercialization assistance program, Concept to Clinic: Commercializing Innovation (C3i) Education. All applications must be received no later than May 25th, 2021.

Introduction to Health Services Research in the Epilepsies Webinar on June 9

The Curing the Epilepsies Conference stakeholders identified Health Services Research (HSR) as a transformative research priority, but noted HSR knowledge and resource gaps.

This CDC/NINDS webinar will provide an overview of Health Services Research (HSR), highlight key HSR epilepsy study approaches and findings, and identify resources to conduct epilepsy HSR studies. No pre-registration is needed, simply join the Zoom meeting at 3:30pm-5:00pm EDT on June 9, 2021.

Department of Defense Program Funding Opportunities For Epilepsy Research Now Open

The Department of Defense Congressionally Directed Medical Research Programs has posted funding opportunities for the FY21 Epilepsy Research Program. Brief descriptions and key elements of the award mechanisms can be found on the website. Letters of Intent are due June 14.

RARE Drug Development Symposium June 9-11

The RARE Drug Development Symposium is taking place virtually June 9-11, 2021. New to this year’s event is an optional pre-conference workshop on June 9, targeted to attendees who are in the early stages of research engagement.

American Epilepsy Society Accepting Abstract Submissions for Annual Meeting through June 9

Submit an abstract by June 9 to be considered for presentation during the AES Annual Meeting. In addition to the in-person poster hall, presenters can expect a virtual presentation opportunity during the meeting.

Nominate Outstanding Epilepsy Professionals for American Epilepsy Society Awards by June 4

AES is accepting award nominations of stand-out epilepsy professionals for significant accomplishments, contributions, and service in the field of epilepsy. to be featured at the 2021 AES Annual Meeting in Chicago, IL. Nominations must be submitted by 11:59 PM PST on Friday, June 4, 2021.

NIH Virtual Meeting on Gene-Targeted Therapies: Early Diagnosis and Equitable Delivery

The National Center for Advancing Translational Sciences (NCATS), the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), and the National Institute of Neurological Disorders and Stroke (NINDS) are co-hosting a virtual NIH roundtable meeting on Gene-Targeted Therapies: Early Diagnosis and Equitable Delivery. The meeting will take place June 3, June 10, and June 17 from 12 – 4:30 PM ET.

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