February 7, 2018

Ketogenic Diet Clinical Trial: The Modified Ketogenic Diet for the Treatment of Pharmacoresistant Epilepsy in Adults, an Observational Cohort Study

This study is a prospective observational cohort study for adult patients with drug resistant epilepsy who are not suitable for resective epilepsy surgery. The intervention is a modified ketogenic diet. The carbohydrate load will be between 20-30gm per day. Blood ketones and blood sugars will be monitored. The primary outcome measure is seizure frequency at 12 months. There are a number of secondary outcome measures including tolerability, seizure severity, quality of life, lipid profiles and health care utilization.

Status: Recruiting
Estimated Study Completion date: September 1, 2018

Eligibility Criteria

Ages Eligible for Study: 18 Years to 100 Years (Adult, Senior)
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Sampling Method: Non-Probability Sample

The study will have no formal inclusion/exclusion criteria as it is purely observational and it will be the clinical team’s decision as to whether or not people are seen by the dietary clinic based on established dietary clinic protocols.