October 30, 2023

CHOP Researchers Develop First-of-Its-Kind Prediction Model for Newborn Seizures

Article published by Pharmacy Practice News

Researchers from Children’s Hospital of Philadelphia (CHOP) have developed a prediction model that determines which newborn babies are likely to experience seizures in the neonatal ICU (NICU). Neonatal seizures are a common neurologic issue in newborn babies. Approximately 30% of newborn babies with a temporary lack of oxygen to the brain (known as hypoxic-ischemic encephalopathy, or HIE) will have seizures. Most of these seizures can only be detected through EEG monitoring and not simply through clinical observation. This model could be incorporated into routine care to help the clinical team decide which babies will need EEGs and which babies can be safely managed in the NICU without monitoring through EEGs. This would allow families and providers to care for babies without intrusive and unnecessary procedures. The study team has made the model available as an online tool for the community.