An increased risk of osteoporosis was observed for patients with epilepsy who use enzyme-inducing AEDs, were on polytherapy with AEDs and had increased duration of epilepsy.
The researchers show that a change in pH disrupts the communication within the intercellular astrocyte networks. This reduced communication between astrocytes appears to exacerbate epileptic activity of neurons.
Several key elements for nocturnal seizure detection devices implementation included the importance of gaining trust and the possibility to adjust seizure detection devices settings for different types of caregivers.
CURE Epilepsy, based in Chicago and Epilepsy Canada, headquartered in Toronto, two organizations at the forefront of funding scientific research, have agreed to form a strategic working relationship.
Genetics
Study finds that mice with a particular GABA-A receptor subunit mutation have increased neuroinflammation in multiple brain regions.
Pediatric Epilepsy
Three quarters of severe epilepsies of infancy could be assigned an epilepsy syndrome or "variant syndrome" at presentation.
Genetics
Researchers identified genes that may contribute to the shared genetic etiology between epilepsy and autism, which could eventually be used for personalized treatment and management.
Although patient-specific variables were the primary determinant of seizure outcomes, cross-national disparities also contribute to heterogeneities in outcomes for patients with drug-resistant epilepsy.
Genetics, Pediatric Epilepsy
The new results indicate that Early Infantile Epileptic Encephalopathy 35 (EIEE35), a neurological disorder characterized by epileptic seizures and associated with deficiency of ITPA, may involve cell membranes becoming more excitable because of depolarization caused by ITPA deficiency.
