We describe a multicenter experience with VNS implantation in pediatric patients with epileptic encephalopathy.
Adrenocorticotropic hormone and oral steroids demonstrated superiority compared with non-standard therapy for the initial treatment of infantile spams in a prospective, multicenter observational cohort study published in Neurology.
Scientists at the Ruhr-University Bochum, Germany, have now discovered a new optogenetic tool and demonstrated its potential in epilepsy research.
The study showed how the use of remote patient monitoring in the form of mHealth can benefit epilepsy patients, despite highly variable engagement with the technology.
Researchers and users of patient-reported outcome measures in epilepsy need to consider the differential interpretation of items for various instruments to ensure valid understanding and comparisons of PROM scores.
The combination of mobile patient reported outcomes and wearable devices generated informative datasets that will allow clinicians but also the children and their caregivers to better understand and manage the disease.
Our results indicate that microglia may not be simply clearing debris but providing structural support for neuronal integrity that may have implications even beyond the scope of seizures and epilepsy.
