Pediatric Epilepsy
The trauma perspective in severe childhood epilepsy might further clarify the complex associations of biological and contextual variables that affect the children's life quality and enable better preventative treatment options for this group.
CBD
Release of the brain’s equivalent of THC, marijuana’s active component, reduces seizure activity but leads to post-seizure oxygen deprivation in the brain, Stanford scientists and their collaborators have shown
Seizure reduction (not freedom) is not good enough to help the patients with TLE enjoy a healthy life with satisfactory social achievements.
Findings suggest that anterior temporal lobectomy patients show a more developed identity profile compared to surgically naïve controls; however, the majority still struggled with postoperative identity change at long-term follow-up
For patients with drug-resistant focal epilepsy, taking into account genetic data has improved clinical decision making and has led to the definition of new disease entities
Breath instead of blood: researchers from the University of Basel have developed a new test method to measure treatment success in epilepsy patients
The aim of this work is to describe a population of pediatric patients with PNES and identify factors predictive of 12-month outcomes.
This study highlights the value of scalp EEG, particularly the significance of interictal epileptiform discharges [activity observed in between seizures], in predicting surgical outcome
Genetics
An evidence-based definition of SCN1A-Dravet syndrome is essential for early diagnosis. We refine the spectrum of Dravet syndrome, based on patterns of seizure onset, type, and progression.