HMGB1 distinguishes with high specificity and selectivity drug-resistant versus drug-responsive patients. This protein therefore has potential clinical utility to act as a biomarker for predicting response to therapy, which should be addressed in prospective clinical studies.
A survey to understand what matters most to families and patients with Dravet syndrome showed that items related to daily life ranked higher than items related to seizures.
Compared with the present modalities used in neuromodulation for epilepsy, focused ultrasound can access deeper brain regions and focus on the main target of the epileptic network in a relatively less invasive approach.
SUDEP
Epilepsy-related deaths are a major public health problem in Scotland, given that they are not reducing, people are dying young, and many deaths are potentially avoidable. Services may need to be re-evaluated to improve specialist referral following seizure-related hospital admissions.
The review of 17 publications concerning miRNAs indicated that there maybe a unique opportunity for disease monitoring and personalized therapeutic management in the future
The results from this study indicate that medium chain triglyceride diet therapy may provide therapeutic benefits in DS
The study also confirmed the researchers’ previous findings that catamenial epilepsy – when seizure frequency increases during a woman’s menstrual cycle – was strongly associated with treatment-resistance generalized epilepsy.
These grants are awarded for novel research projects that address finding cures for epilepsy and address the goal of “no seizures, no side-effects.”
