Disease-causing variants in STXBP1 are amongst the most common genetic causes of neurodevelopmental disorders. However, the phenotypic spectrum and outcomes in STXBP1-related disorders are wide, and clear correlations between variant type and clinical features have not been observed so far.
Building on prior evidence, diagnostic delay in patients with new-onset focal epilepsy has been identified as an important problem for patients with epilepsy. Such delay in diagnosis can lead to delayed treatment and potentially preventable morbidity and mortality including motor vehicle accidents.
People with epilepsy face serious driving restrictions, determined using retrospective studies. To relate seizure characteristics to driving impairment, we aimed to study driving behavior during seizures with a simulator.
People with epilepsy face serious driving restrictions, determined using retrospective studies. To relate seizure characteristics to driving impairment, we aimed to study driving behavior during seizures with a simulator.
Biomarkers of neuronal damage in status epilepticus (SE) would be of great relevance for clinical and research purposes.
Vigabatrin (VGB) is the first-line treatment for infantile spasms (IS). Previous studies have shown that VGB exposure may cause vigabatrin-associated brain abnormalities on magnetic resonance imaging (MRI) (VABAM).
Prior studies in the field of epilepsy surgical disparities have examined barriers in undergoing epilepsy surgical resections in disadvantaged populations involving trust in health providers, education level, social support, and fear of treatment.
This month’s research news features two studies examining the underlying causes of epilepsy, and more.
