Genetics, Pediatric Epilepsy
A large-scale case-control study implicates genes critical for fever response and genes for communication between nerve cells.
A study published recently in the Journal of Neuroscience provides a remarkable finding that may help physicians diagnose epilepsy before the first seizure: People with temporal lobe epilepsy (TLE) have difficulty distinguishing the present from the past.
There is no effective therapy to prevent the development of posttraumatic epilepsy (PTE). Recently, we reported that administration of the antiseizure medication (ASM) levetiracetam (LEV) shortly after trauma prevented the development of epileptiform activity in two experimental models of neurotrauma.
Research from the UVA School of Medicine suggests how a newly developed gene therapy can treat Dravet syndrome, a severe form of epilepsy, and potentially prolong survival for people with the condition.
In order to more appropriately apply and understand the “epilepsy treatment gap” (ETG) concept in current health systems, revised conceptual and operational definitions of ETG are timely and necessary. This article therefore systematically reviews worldwide studies of the ETG, distinguishing high-, middle-, and low-income regions, and provides recommendations for an updated International League Against Epilepsy (ILAE) definition of ETG.
A research group led by professor Ko Matsui from the Super-network Brain Physiology Lab at Tohoku University reported on a stimulation paradigm used on experimental animals that could potentially cultivate resilience to epilepsy.
An assistant professor at The University of Texas at Arlington has developed a wearable headset that detects when epilepsy patients are having seizures and records data that doctors can monitor and review.
Pediatric Epilepsy
To evaluate how racial disparities in medication adherence barriers relate to key clinical outcomes (i.e., seizure control and adherence) in pediatric epilepsy and to identify the most critical barriers in determining health outcomes in Black youth and White youth.
This month we highlight new research advancing our knowledge of epilepsy genetics, epilepsy risk factors, new treatment targets, and more.
