Brain oxygenation during and following a febrile seizure has a distinct pattern and multiple mechanisms. Brain oxygen dynamics may be an important consideration in the development of treatments for febrile seizures.
The research, by Miraç Y?ld?r?m and colleagues, investigated characteristics in children with epilepsy who had become seizure free with epilepsy medicines and who were able to come off their medicines. They wanted to find out if any characteristics could be used to predict whether the children would end up having returning seizures.
Two of the five patients (40%) in the experimental arm were successfully treated with ketamine and two of the five (40%) children in the control arm, where successfully treated with thiopental. In the remaining six (60%) enrolled patients, RCSE was not controlled by the randomized anesthetic(s).
Pediatric Epilepsy
The objective of this systematic review is to summarize, evaluate, and quantify outcome metrics for the surgical treatment of pediatric epilepsy that address seizure frequency, neuropsychological, and health-related quality of life (HRQL).
A team of Florida State University College of Medicine researchers has found a link between a specific protein in the brain and increased vulnerability to neurodegeneration for individuals with temporal lobe epilepsy (TLE).
The National Institute of Neurological Disorders and Stroke (NINDS) has awarded Emory neuroscientists a three-year, $2 million grant to develop new anti-inflammatory drugs for the prevention of comorbidities related to epilepsy.
Pediatric Epilepsy
Results showed that ketamine infusion was followed by seizure termination in 32 patients, seizure reduction in 19 patients and no change in 18 patients. Data also revealed three patients had adverse events requiring intervention during or within 12 hours of ketamine administration, including hypertension in two patients and delirium in one patient.
Young stroke patients who have a seizure following their diagnosis are two and a half times more likely to develop dementia than patients who don’t experience seizures, according to a new study by Penn State College of Medicine researchers. They said their results warrant further study into whether monitoring and treating young stroke survivors — those 60 years old and younger — for seizures can slow or prevent dementia onset and progression.
Experts recently found reduced brain volumes in pediatric patients who had previously sustained serious head injuries. New work published in Brain details how researchers concluded that both gray and white matter volumes decrease relative to head size during adolescent development.
