Genetics
Affected girls and women should be carefully monitored for later?onset psychiatric disorders, researchers suggest.
Discover the latest about what's happening at CURE and in our community in the March 2019 CURE Update from Chief Scientific Officer, Laura Lubbers!
Pediatric Epilepsy
The Violet Study is intended to support the regulatory filings for approval of ganaxolone in this underserved and refractory patient population.
Ketogenic Diet, Pediatric Epilepsy
Children achieving drug-free diet therapy were more likely to be younger, have fewer antiseizure drugs at ketogenic diet onset, have Glut1 deficiency or epilepsy with myoclonic-atonic seizures, but were less likely to have Lennox-Gastaut syndrome or a gastrostomy tube.
Patients with epilepsy who respond to eslicarbazepine acetate (ESL), have a seizure frequency reduction (SFR) of greater than or equal to 75%, and are at the lower SFR threshold of greater than or equal to 50% have higher health-related quality of life (QoL) compared with nonresponders to ESL.
Study designs allowing for long-term comparative observations would be of great value, but are hindered by the inherent nature of a long-term [surgical] control group and the bias associated with open-label trials.
Based on aggregated clinical data analytics, the project will provide insights into disease progression and responses to treatment.
This webinar discusses how epilepsy patients, their families, and pediatric neurologists can develop a plan to prepare for the transition of care.
Researchers find that perampanel increases assessment scores indicative of aggression as well as depression.
