Patients who had a minimally invasive evaluation procedure experienced fewer complications, and those who went on to have brain surgery were more likely to be seizure-free than patients who had the more invasive evaluation procedure.
This screening questionnaire showed a significantly lower level of sensitivity when validated in the field, confirming that hospital?based validation can lead to an overestimation of sensitivity.
This study found an increase in the excitatory synaptic function and decrease in the inhibitory synaptic function only in CASK mutant neurons, but not in wild-type neurons in the same brain.
A minimally invasive procedure to determine whether patients with drug-resistant epilepsy are candidates for brain surgery is safer, more efficient, and leads to better outcomes than the traditional method.
Genetics
Affected girls and women should be carefully monitored for later?onset psychiatric disorders, researchers suggest.
Discover the latest about what's happening at CURE and in our community in the March 2019 CURE Update from Chief Scientific Officer, Laura Lubbers!
Pediatric Epilepsy
The Violet Study is intended to support the regulatory filings for approval of ganaxolone in this underserved and refractory patient population.
Ketogenic Diet, Pediatric Epilepsy
Children achieving drug-free diet therapy were more likely to be younger, have fewer antiseizure drugs at ketogenic diet onset, have Glut1 deficiency or epilepsy with myoclonic-atonic seizures, but were less likely to have Lennox-Gastaut syndrome or a gastrostomy tube.
Patients with epilepsy who respond to eslicarbazepine acetate (ESL), have a seizure frequency reduction (SFR) of greater than or equal to 75%, and are at the lower SFR threshold of greater than or equal to 50% have higher health-related quality of life (QoL) compared with nonresponders to ESL.
