Genetics
The research team claims that their results pave the way for exploiting dCas9-based gene activation as an effective and targeted approach in Dravet syndrome and other disorders resulting from altered gene dosage.
In this article, Dr. Louis Nemzer describes how novel approaches to predicting and treating seizures are being developed thanks to advances in our understanding of the physics of the brain.
Epilepsy duration is the only known predictor of seizure-freedom following surgery that can be influenced, so this study underlines the importance of people with drug resistant epilepsy being investigated for a possible epilepsy operation as soon as possible.
Genetics
This study contributes a novel candidate gene in periventricular nodular heterotopia generation and a novel practical approach that integrates electrophysiological and genetic explorations of epilepsy.
SUDEP
A new study finds that serotonin may provide a clue.
CURE Update: Discover New Research and Attend Community Events
Pediatric Epilepsy
Diacomit is a new type of anticonvulsive medication that has been shown to reduce the frequency of seizures in patients with Dravet syndrome, especially when administered in combination with other antiseizure medications or with dietary interventions.
NIH awards $2.3 million to Dr. Nuri Ince to expand testing to dramatically decrease in the time it takes to detect the seizure onset zone (SOZ) in the brain
The aim of this systematic review is to synthesize the evidence regarding the perspectives of children and adolescents with PNES, and the perspectives of their parents, caregivers and families.
