From live streams to kids' activities, there's plenty happening around the CURE community this month!
Pediatric Epilepsy
Researchers generated a KCNQ2?related epileptic encephalopathy mouse model to study the pathophysiology and perform preclinical research.
According to the authors, this study established a simple, practical, and evidence-based prediction score for predicting seizure freedom with antiepileptic drugs to aid in the clinical consultation and treatment decision for the newly diagnosed patients with MRI-negative epilepsy.
Here, the authors describe the preclinical basis for applying interneuron transplantation to human epilepsy, discuss its potential clinical applications, and consider the translational hurdles to its development as a surgical therapy.
Pediatric Epilepsy
Initial data suggest that soticlestat continues to be safe and well tolerated and appears to reduce seizure frequency in a majority of the individual patients.
During the COVID-19 pandemic, CURE remains laser-focused on funding critically-needed research to drive science closer to a cure for epilepsy.
An increased risk of post-traumatic epilepsy is associated with higher age, moderate severity of injury, obliterated suprasellar cisterns, seizures during ICU stay and surgical care.
For her 75th birthday, CURE Champion Mary Fox hosted a 26 day virtual marathon in honor of her granddaughter who has epilepsy.
This study aimed to develop personalized forecasts from a mobile seizure diary app, since seizure cycles can be measured using a range of recording modalities.
