Pediatric Epilepsy
According to the researchers, therapeutic hypothermia was found to be “safe for use in pediatric patients with refractory status epilepticus or super-refractory status epilepticus
The duration of focal seizures was prolonged with increasing age of the patients and was significantly shortened by secondary spread.
The assay of saliva samples provides a valuable alternative to the use of blood samples for therapeutic drug monitoring (TDM), at least for certain categories of patients.
Psychoeducational interventions appear to have had positive results in Argentinian patients with PNES.
According to available literature, the global clinic-based lifetime prevalence of epilepsy in individuals with Down syndrome ranged from 1.6% to 23.1%, with epileptic spasms representing 6.7% to 66.7% of these cases.
This is the first study to provide objective evidence for a considerable negative effect of ZNS treatment on executive function, according to study authors.
The team demonstrated that both mutations lead to a significant gain in channel activity, and they observed a higher sensitivity to stimulation by an endogenous neurosteroid and heat.
Older US veterans who developed unprovoked seizures of unknown cause had double the risk of developing dementia over several years of follow-up.
Independent of current depression, use of pregabalin (Lyrica®) in the younger group and frequent seizures in the older group were associated with a risk of suicide.
