Rare Epilepsies
There is an opportunity for further research aimed at developing more innovative GABA-targeting therapies.
Ketogenic Diet
This review will cover the history, clinical trials, implementation, current utilization, and future directions of this "alternative" ketogenic diet therapy on its 20-year anniversary.
Genetics
While genetic testing to help determine the cause of epilepsy is possible, comprehensive testing does not always happen routinely and it can take a long time, leaving families waiting for answers.
Mechanisms
“These findings not only deepen our understanding of how seizures originate but are expected to have a wider impact on several neurological diseases."
Adult-onset
As a large population of patients with epilepsy ages, risk of hyponatremia has become an important clinical concern, in which monitoring of serum sodium levels when receiving antiseizure medications or antipsychotics (ASMs) may help identify and minimize the risk of hyponatremia in patients with epilepsy.
Treatment
The current review presenting a list of plants with antiepileptic effects aims to pave the way for finding alternative drugs with fewer side effects for scientists.
Treatment
Intra-operative seizures (IOS) can occur during awake craniotomies (AC) for brain tumors. They can potentially result in an increased risk of morbidity; however, literature is scarce on IOS, its risk factors, and predictors.
Genetics, Mechanisms, Treatment
Our understanding of the genetics and pathophysiological mechanisms underlying HCN1 epilepsy has progressed significantly and is already influencing therapy.
Rigorously designed biomarker studies with methods acceptable to the regulatory bodies should be conducted.
