Taking Flight Award

Seizure Generator Location And Antiepileptic Drug Efficacy

Jeffery Tenney, MD, PhD
Cincinnati Children’s Hospital Medical Center

Absence epilepsy is the most common type of pediatric epilepsy syndrome and up to half of children impacted fail the best initial treatment. Response to treatment may depend upon whether seizures begin on the surface of the brain or in deeper structures. The goal of Dr. Tenney’s research is to use state-of-the-art neuroimaging to compare areas of seizure onset in children with medication responsive and non-responsive epilepsy. This information will then be used to review the initial EEG for patterns that could predict treatment response. Better understanding of these differences will lead to reduced seizure burden and medication side effects.


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