The Rhode Island Award

Identification Of Potential Gene Targets For Cortical Dysplasia

Gabriella D’Arcangelo, PhD
Baylor College of Medicine, Houston

This study will conduct a molecular characterization of the abnormal neurons found in brain tissue resected from patients with focal cortical dysplasia (FCD). Gene expression profiles of abnormal neurons will be generated using cutting edge technologies such as laser capture microdissection and microarray analysis. This research will provide the necessary groundwork for designing future studies aimed at reducing or eliminating seizures in cortical dysplasia patients.


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