Challenge Award, Funded by the Julie's Hope Award

Flexible, Active, Implantable Devices for Epilepsy

Brian Litt, MD
University of Pennsylvania

Dr. Litt and his coworkers developed a new implantable brain device to map, analyze and control epileptic networks on a much finer scale than has previously been possible. The new devices contain thousands of high-resolution sensors and “effectors” that can measure electrical, optical and other signals in brain tissue over clinically relevant scales. The devices are built on dissolvable materials that cause them to closely adhere to the brain’s irregular surface. With funding from CURE, they will further develop these devices and test them first in animal models and then in individuals with medically resistant epilepsy in pursuit of CURE’s mission to achieve “no seizures and no side effects.”


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