CURE - Citizens United for Research in Epilepsy It's Time We Found a CURE CURE Epilepsy Research



Question How many grant cycles does CURE have per year?
Answer There are 2 grant cycles:
Taking Flight - The Taking Flight Award seeks to promote the careers of young epilepsy investigators to allow them to develop a research focus independent of their mentor(s).

Innovator - This award explores a highly innovative new concept or untested theory that addresses an important problem relevant to epilepsy.

Challenge - This is a prestigious award for research in one of our priority areas: the basic mechanisms of epileptogenesis or the multifaceted causes of epilepsy.

Pediatric Epilepsies - This award funds research projects of relevance to any or all of the epilepsy syndromes that occur in the pediatric population.

Prevention of Acquired Epilepsies - This award funds research relevant to the prevention and elimination of acquired (post-insult) epilepsies, including epilepsy caused by traumatic brain injury (TBI), stroke, infection, and tumor.

SUDEP - This award funds research projects that will address the goal of understanding and eliminating SUDEP.


Question What are the current open funding opportunities at CURE?
Answer There are 4 awards in our active grant cycle:
- Challenge
- Pediatric Epilepsies
- Prevention of Acquired Epilepsies
Question What are the funding levels and budget restrictions for the current grant cycle?
Answer Challenge Award:  up to $250,000 used over 2 years
Pediatric Epilepsies Research Award:  up to $250,000 used over 2 years
Prevention of Acquired Epilepsies Award:  up to $250,000 used over 2 years
SUDEP Award:  up to $250,000 used over 2 years
Question What are the key dates for the current funding cycle?
Deadline for Receipt of LOI:  January 15, 2015
Full Application Invitations: February 27, 2015
Deadline for Receipt of Full Application: May 5, 2015
Award Announcement: July 2015
Earliest Project Start Date: August 1, 2015
Question What should I list as the start date for the project?
Answer The earliest start date for the Challenge, Pediatric, Prevention of Acquired Epilepsies, and SUDEP Award is August 1, 2015.


Question Can I apply for a CURE grant at any time?
Answer Unfortunately no. CURE does not accept unsolicited proposals. Researchers interested in applying for a grant must first submit a Letter of Intent (LOI). Calls for LOIs are announced on CURE’s website and via email, so please be sure to check the website regularly. You may also contact us to have your name added to our email list.
Question Who can apply for a CURE grant?
Answer CURE GrantsFor most CURE awards, both established and early-career investigators may apply. The CURE Taking Flight award is specifically designed for advanced postdoctoral fellows, neurology fellows, and new faculty who are beginning to transition to independent investigators.

Please refer to the CURE website for information on who specifically qualifies to apply for each of our grant categories.
Question How do I determine if I am an early-career or established investigator?
Answer Generally, early career investigators are university faculty at the assistant professor level (or hold an equivalent position in a non-university research organization). Established investigators are university faculty at the associate professor level or above.
Question I am a postdoctoral fellow. Can I apply to the Challenge/Pediatric/ Prevention of Acquired Epilepsies/SUDEP Award?
Answer No. Only independent investigators can apply.
Question I applied last year, but was not awarded funding. I have addressed the concerns voiced in the reviews of my original application and would like to reapply. Can I reapply, and if so, what is the process?
Answer Yes, you are welcome to reapply. However, you must go through CURE’s standard application process. The first step is to submit a Letter of Intent (LOI).
Question I’ve received a grant in the past. Can I apply again?
Answer Yes. You are welcome to apply for a grant as a current/former CURE grantee. It should be noted, though, that a current grantee cannot receive funding on two different awards at the same time. S/he is welcome to apply for a new award as long as funding for the new award would begin after the current award has ended.

As with all applicants, you must go through CURE’s standard application process. The first step is submitting a Letter of Intent (LOI).
Question Are international applicants eligible to apply?
Answer Yes, international applicants are eligible to apply for CURE grants. All application materials must be submitted in English and should be written with a clear hypothesis and specific aims as is consistent with the U.S. grant making system.
Question I was/am a reviewer. Can I still apply?
Answer If you have previously reviewed for CURE, you may submit an application. You will be ineligible to review during the cycle in which you submit an application.
Question Are multiple researchers from the same institution allowed to apply for the same grant?
Answer Yes. There is no limit to the number of researchers from the same institution who can apply for the same grant.
Question Can I submit more than one grant application in the same cycle?
Answer Yes, if the two applications have completely different hypotheses and specific aims. You may not submit the same grant to multiple categories at the same time.
Question Does CURE fund only academic laboratories?
Answer CURE funds research from academic and non-academic laboratories. We fund researchers working at universities, companies, and non-profit research institutions.


Question What information should I include in the Letter of Intent (LOI)? Are there any length restrictions?
Answer Letter of Intent Instructions: In your uploaded letter of intent, please provide the following:
  1. Your LOI will be reviewed by members of CURE’s Lay Review Council. Using non-scientific language (1/2 page maximum), please provide the following:
    • Project Goals: Bulleted list of the goal(s) of the project.
    • Aims: Bulleted list of how those goals will be tested.
    • Deliverables: Bulleted list of tangible deliverables to result from this work if successful.
    • Impact: Briefly explain how this project, if successful, will transform the field of epilepsy and contribute to improved treatment and prevention.
  2. Provide a brief description of the research plan that succinctly outlines the hypothesis and specific aims of the proposed research (1 page maximum).

All LOIs are evaluated for innovation, feasibility, scientific merit, relevance to grant mechanism, relevance to CURE’s mission, and potential to be transformative.
Question Are there formatting requirements for the Letter of Intent (LOI)?
Answer Yes, you will find this information outlined in the Letter of Intent (LOI) guidelines.  For quick reference:

Formatting Guidelines:
  • Type font: 12 point, 10 pitch
  • Type density: No more than 15 characters per inch (including spaces). For proportional spacing, the average for any representative section of text should not exceed either 15 characters per inch or 114 characters per line.
  • Spacing: Single-spaced between lines of text, no more than five lines of type within a vertical inch.
  • Margins: Minimum of 0.5-inch top, bottom, right, and 1-inch left.
Question I'm an international applicant and some of my application materials are in a language other than English. Can I still submit them?
Answer No. All application materials must be submitted in English.


Question How do I submit my Letter of Intent (LOI)?
Answer All LOIs must be submitted through the proposalCENTRAL online application system (  LOIs that are emailed, mailed, or faxed will not be accepted.
Question I am trying to submit my LOI but every time I click on CURE in proposalCENTRAL it takes me to the CURE homepage. Why is this happening?
Answer In order to begin an application, you will need to create a professional profile in proposalCENTRAL. Once you have done so, an 'Apply Now' button will appear at the far right. When you click this button, you will be taken to the application section of the portal.
Question If I can't submit by the posted deadline, can I request an extension? What is CURE's policy on late submissions?
Answer No, CURE does not accept late applications.
Question When will I know if I am invited to submit a full proposal?
Answer CURE will send accepted and declined notifications via proposalCENTRAL once the LOI review process is complete. This typically takes place approximately 4- 6 weeks after LOIs are submitted.
Question If I am submitting with another researcher, do we both need to submit an application?
Answer CURE welcomes collaborative proposals with more than one principal investigator. However, one application must be submitted on behalf of the collaboration, under one PI's account in proposalCENTRAL.
Question Once I have submitted my application, can I check on its status?
Answer Applicants can check updated status of their applications by logging into their accounts on proposalCENTRAL. All applicants will be notified as soon as application decisions are made.
Question How quickly will the full proposal be reviewed? When can I expect to know if my application has been chosen for funding?
Answer The review and approval process at the full proposal stage typically takes 10-12 weeks to complete (from receipt of full proposals to announcement of awards).
Question If not chosen for funding, how can I get feedback on my application?
Answer Critiques on full proposals will be available in your proposalCENTRAL account after the review cycle is complete.


Question Can multidisciplinary funding be split between two institutions?
Answer Yes, funding can be split among multiple institutions. However, CURE will only contract with the primary institution, which will be responsible for negotiating subcontracts with any collaborators/co-PIs at additional institutions. CURE requires detailed budgets outlining the allocation of funds to each institution.
Question Who can receive salary from the grant?
Answer Grant funds can be allocated to cover the salaries of investigators, postdocs, and graduate students in relation to percentage of effort spent on the project, as well as research supplies and some travel (see below). Indirect costs are not covered.
Question Can grant funding be used for travel?
Answer Yes. $1,000 per year can be allocated for travel; $1,500 can be allocated for international grantees.
Question Can the budget include indirect costs?
Answer No. CURE does not provide funding for indirect costs.
Question I’m an international applicant and some of my application materials are in a language other than English. Can I still submit them?
Answer No. CURE does not provide support of indirect costs.





CURE For questions, please contact Julie Milder at the CURE office, 312.255.1801, or email

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